Odontogenic ghost cells: Realities behind the shadow….

The realities behind the polls.

Aggressive Recurrent Odontogenic Ghost Tumor with Cranial Invasion.

Calcifying odontogenic cyst (COC) is a unique odontogenic lesion with combined features of a cyst and neoplasm.  This lesion shows a great diversity in its clinicopathological behavior.  It may become aggressive and rarely malignant.  This case is an aggressive COC of the maxilla in a young male patient which recurred after several radical surgical excisions.  Eventually invading the cranium, t...

Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report

Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in...

Pediatric Metastatic Odontogenic Ghost Cell Carcinoma: A Multimodal Treatment Approach

Odontogenic ghost cell carcinoma (OGCC) is a rare and aggressive tumor wherein optimal treatment remains uncertain. We report the first pediatric metastatic OGCC case treated with multimodal therapy: surgery, adjuvant chemoradiation, and adjuvant immunotherapy. Adjuvant therapy was utilized due to locally advanced disease with pathologic features indicative of high recurrence risk. This multimo...

aggressive recurrent odontogenic ghost tumor with cranial invasion.

calcifying odontogenic cyst (coc) is a unique odontogenic lesion with combined features of a cyst and neoplasm.  this lesion shows a great diversity in its clinicopathological behavior.  it may become aggressive and rarely malignant.  this case is an aggressive coc of the maxilla in a young male patient which recurred after several radical surgical excisions.  eventually invading the cranium, t...